Hangovers – Electrolytes

Last week, we talked about what a hangover is, what its symptoms are and why hangovers cause headaches. This week, we’ll take a brief look at the importance of electrolytes in relation to hangovers.

A little recap

A little while ago, we talked about how alcohol inhibits a hormone called the antidiuretic hormone, which is the hormone that allows the body to reabsorb water from our kidneys before the kidneys send the final solution to our bladders for release. With this inhibition, not only is there not enough water reabsorbed but, because this hormone is inhibited, we urinate frequently under the influence of alcohol.

Now where do electrolytes fit in?

As a result of this frequent urination, we lose more than just water from our bodies. In addition to water, we lost electrolytes like sodium and potassium.

These electrolytes are important for several processes in our bodies, including nerve and muscle functions. When you lose a lot of electrolytes, your nerve and muscle functions are weaker as they require the electrolytes to help propagate signals. This is why you feel tired the morning after a rowdy night.

The absence of electrolytes also leaves you feeling nauseous and with an awful headache because of how dehydrated you are.

Help me, what can I do?

There was a post I did a million years ago (it was last July) where I talked a bit about electrolytes. Here’s the deal with them: where electrolytes go, water goes. So it’s time to power up with some electrolytes because the more electrolytes there are in your body, the better your body will retain water and the easier it will be to rehydrate! So grab some sports drinks, make sure it has some potassium in it, and rehydrate! You’ll feel like a normal being soon enough 🙂

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Hangovers – Headaches

Hello Children, it’s time to learn about one of the many upsetting effects of alcohol. Okay, I know most of you are probably people actually going through a hangover and you want to know why this is happening to you… I mean, you’re a good person (probably). So why oh why is last night hurting you today?

What is a hangover?

Unlike the movie ‘The Hangover’, where the characters pretty much go on an adventure the day after a rowdy night with seemingly no physical repercussions other than a couple tattoos, a hangover would probably make you want to sleep for a whole day.

A hangover, formally called a veisalgia, is basically the umbrella term for the after effects of drinking. It includes headaches, body aches, tiredness, weakness, thirst, nausea (sometimes vomiting), general stomach pain, diarrhea, and a slew of other symptoms like depression, vertigo and decreased attention.

Of course, you won’t likely experience all of these symptoms at once! There are different hangovers and they depend on how much you drink and how well your body is at detoxifying the alcohol. If you drink a lot and your body detoxifies alcohol at a very slow rate, then you will likely have an extremely bad hangover (unless you take some precautions – which will be explored in a later post!).

Why do we get hangovers?

If you recall last week’s post, where we discussed the effects of alcohol on the body, alcohol inhibits a hormone. This hormone, the antidiuretic hormone, is responsible for the reabsorption of water by your body’s kidneys. Without the activity of this hormone, the water that would have been retained by your body goes straight to your bladder and is then excreted. This loss of water results in your body becoming dehydrated, which leads to you getting a hangover.

Headaches and Hangovers, oh my!

Even though you are consuming a form of liquid, the amount of alcohol consumed is not as much as the amount of water lost during urination. This dehydrated state is what causes your headache, as the organs in your body are trying to their best to retain as much water as possible – even if that means stealing water from your brain. This results in your brain shrinking in size, making the membranes that connect your brain to your skull stretch – thus your headache. Crazy, huh?

Next week, we’ll talk about the relationship between Electrolytes and Hangovers.

Alcohol and Urine

For the last couple of weeks, I’ve talked to you about pee… a lot. But now that we’ve got all of that good stuff down pat, it’s time to get to the point of this whole thing: the effects of alcohol on urine!

Whenever you drink alcohol, you eventually feel the need to urinate frequently. But why?!

Well, last week we learned about the two hormones that are involved in regulating the production of urine: the antidiuretic hormone and aldosterone.

Interestingly enough, alcohol has an inhibitory effect on the antidiuretic hormone. This hormone is responsible for helping the body retain water by preventing the loss of water through excretory pathways, like the urine system.

The inhibition of the antidiuretic hormone results in the loss of regulating how much water is reabsorbed in the kidneys, which means that there is an uncontrollable loss of water in your urine, which is why you feel the need to urinate a lot. Your bladder is always filled because there is no reabsorption of water in the nephron of your kidneys.

So basically, alcohol reduces the amount of water reabsorbed in the kidneys, which leads to the water ending up in your bladder and putting pressure on your urinary sphincters. And then you feel the need to urinate, even if you already went to the bathroom 10 minutes ago.

One of many life’s mysteries have been solved. The inhibition of the antidiuretic hormone by alcohol is another reason why rehydration is so important for post-drinking. You lost all of the water your body would have reabsorbed when you peed, so you need to drink even more water to save your body from being in a state of dehydration.

And that’s how alcohol affects your body’s urinary system! Next week, we’ll look into hangovers.

The Urinary System – Concentration and Dilution

Last time, we talked about how the urinary system allows for our bodies to selectively reabsorbs things that were filtered out of our circulatory system. One of the molecules that can be reabsorbed is water, which is an important molecule for several reasons. In terms of the urinary system, water is important for the concentration and dilution of our urine.

The concentration and the dilution of urine is regulated by 2 hormones: Anti-diuretic hormone and Aldosterone.

The anti-diuretic hormone is released if you’re dehydrated, and literally translates to “against the passing of urine”. In situations where you are dehydrated, your blood volume will be low due to the lack of a sufficient amount of water, resulting in a lower blood pressure. To counteract this, the anti-diuretic acts to reduce the amount of water lost by the body and minimizes how much urine you make and release. This will result in a more concentrated urine that has a less water than usual and is a deeper yellow due to the higher concentration of urea.

Aldosterone is also released when you’re dehydrated. This hormone is responsible for the increase in thirst while also helping your body retain water by increasing the amount of sodium in your body. The more solute there is in your body, the more likely water is to stay with the solute (rules of osmosis, hurray!).

These hormones exert their effects primarily on the distal tubule of the nephron (after the loop of Henle), so that is where the water is reabsorbed!

So when these hormones are released, your urine will be more concentrated because water is retained by your body! Amazing, right?

Next week: We will finally get to talking about the effect of Alcohol on Urine!

Is there something you’d like to learn about? Tell me about it here and I may just do a post about it 🙂

The Urinary System – Selective Reabsorption

Last week, we learned about the general filtration process that occurs in our kidneys. This week, we’ll learn just how our kidneys modify the filtrate to produce urine.

The filtrate that is in the renal tubule consists of water as well as other small molecules, like sugars and urea. Some of these molecules, like sugars, can return to the bloodstream in a ‘process’ known as selective reabsorption. It’s called ‘selective’ reabsorption because the bloodstream is picky as to what it absorbs from the tubule. The molecules that leave the tubule enter tiny blood vessels next to the tubule, which are called peritubular capillaries. The molecules can then be carried through the rest of the circulatory system, to provide our body cells with nutrients (if they’re sugars).

Parts of the Kidney

Selective reabsorption mainly occurs in the proximal tubule, which is the beginning of the tubule. The proximal tubule is just after the Bowman’s capsule. Whenever a molecule leaves, it is accompanies by water, which means a lot of water is reabsorbed by the bloodstream in this process.

By returning the molecules to the bloodstream, the remaining filtrate’s composition changes. As water leaves, the concentration of particles in the tubule increases.

Hormones can affect what is reabsorbed in the distal tubule. These hormones are the anitidiuretic hormone (ADH), which is also known as vasopressin, and aldosterone. They’ll be discussed next week when we talk about Concentration and Dilution!

The Urinary System – Filtration

Last week, we talked about the basics of the urinary system, including the organs involved. This week, let’s take a closer look at what happens in the kidney, starting with filtration. The posts will be segmented because there will be a lot of new terms coming your way, and I would hate for you to get overwhelmed! So let’s learn how our bodies makes our pee, step by step.

Parts of the kidney

The basic functional unit within the kidneys is known as the nephron. This consists of all of the numbered portions, starting at the glomerulus (5) and ending at the distal tubule (6). 

The main components involved in filtration are the arteries, and the glomerulus.

Filtration

It is at the Bowman’s capsule where the filtration of blood occurs. The blood from the renal artery (renal means ‘kidney’) flows into a smaller version of an artery, known as the afferent arteriole. The name sounds weird, but ‘afferent’ basically means ‘towards something’. So this arteriole is moving blood towards the glomerulus. So this arteriole can also be referred to as the afferent glomerular arteriole.

The afferent arteriole then branches to form tiny blood vessels known as capillaries. These capillaries form a ball-like structure, which is part of the glomerulus (5). The capillaries are therefore called the glomerular capillaries.

The blood from the capillaries continues to flow into the next vessel, which is another arteriole, named the efferent arteriole. ‘Efferent’ means ‘away from something’, so the blood is moving away from the glomerulus. So this arteriole can also be referred to as the efferent glomerular arteriole.

This movement of the blood increases the amount of pressure within the capillaries, causing fluids to leak out. These fluids pass through a filter-like membrane, known as the glomerular basement membrane. Some substances are too large to pass through the basement membrane and, therefore, continue to circulate through the bloodstream.

The filtrate that goes through the glomerular basement membrane enters the Bowman’s capsule. The space inside the Bowman’s capsule is continuous with the rest of the tubule, which includes the proximal tubule, the loop of Henle and the distal tubule. The filtrate is concentrated and modified within these components of the tubule, which will be discussed next week.

And that is, thankfully, all there is to the filtration process for the urinary system! Next week, we’ll learn about what happens to the filtrate in the tubule.

The Urinary System – Basics

Before we can talk about how alcohol affects your urinary system, it’s important to understand the urinary system and how it usually works first. This will be a pretty general overview, though I will also provide a molecular overview of the system next week!

So let’s start learning about how urine is made!

The Urine Pathway

The organs involved in your urinary system:

  • Liver – synthesizes urea and releases it into the blood
  • Kidneys – filters the blood for urea, sodium, bicarbonate and water. If they are high levels of any of them, the kidneys will divert them from the bloodstream, and produces urine.
  • Bladder – the products of urine move from the kidney to your bladder, then to the urethra to be released.

The bladder actually has two muscles that control the release of urine: the internal and external sphincter. The internal sphincter relaxes on its own accord, thanks to your sympathetic nervous system. It is the external sphincter that helps you control whether you pee your pants or not.

And those are the basics of the urinary system! Next week, we’ll be looking at the detailed pathway (for you keeners (: ).

Alcohol – Effects on the Body

I’m a university student and you can bet that I’ve seen a lot of people under the influence of alcohol. They can be loud, giggly, emotional, and sometimes really tired.

I wanted to see just what effects alcohol has on our bodies, so posts about the different effects of alcohol will be popping up every now and then. For now, I thought it would be cool to see the list of effects alcohol has been found to have on our bodies.

Some of these effects are real extremes, so take them lightly. 🙂

List of the effects of alcohol on our body

Short-term effects

  • Nausea
  • Diarrhea
  • Makes you urinate more frequently (stay tuned, we’ll be talking about this one shortly!)
  • Flushed appearance
  • Reduced cognitive and motor skills(which is why you shouldn’t drink and drive!)
  • Loss of inhibitions and more confidence
  • Blurred vision (aka beer goggles) and slurred speech
  • Intense moods, e.g. aggression, elation, depression
  • Headache
  • Blackouts
  • Alcohol poisoning, which is really lethal

Diseases/conditions (in extreme cases!!!)

  • Can lead to the development of heart disease after long-term excessive use.
  • Potential cancer developing effects
  • May cause pancreatitis, which can lead to the development of diabetes
  • Liver disease
  • High blood pressure
  • Depression and/or anxiety
  • Weakened immune system
  • Anemia

Effects on our reproductive systems?!

  • Linked to damaging fertility (extreme case)
  • Small amounts of alcohol can affect a woman’s menstrual cycle
  • Alcohol can reduce the amount of testosterone a man produces
  • May affect the quality of a man’s sperm

And this is just a sampling of all of the effects of alcohol. In a couple of weeks, we’ll be talking about urination so that we can get to explore the effects of alcohol on it the week after :).

So, take it easy with eggnog for now, ladies and gents. No need to binge drink, it may just lead to some unhealthy effects!

I will be on hiatus until the first week of January, due to the holidays but Happy holidays and Happy New Year 🙂 Stay safe!

Prostate

When I hear November, I think ‘Movember’. The month of the ‘staches. And just like their moustaches, females are unable to have the type of cancer that the month raises awareness for: prostate cancer. But what is the prostate? What does it do normally? Warning: Children, talk to your parents if you’re reading this. There’s a wee wee on here.

What is the prostate?

The prostate is an organ only found in men. It sits below the bladder and wraps around the urethra (which is a tube that carries urine [and sperm for men] from the bladder to the external environment). It has three lobes: the left, center and right lobes, and is part muscle and part glandular.

Now pick up a walnut. That’s approximately the size of a man’s prostate. That’s pretty small for an organ!

So what does this walnut-sized organ do?

The prostate is important for secreting fluid that is slightly alkaline, which will form part of the seminal fluid. The seminal fluid is the fluid that carries sperm from the urethra to the tip of the penis.

The prostate also helps in male climax (or orgasm). Its muscular portion will help the propelling of sperm and its own secreting fluid into the urethra, where it will then exit.

The Male Reproductive System, including the prostate.

The growth of cells in the prostate is stimulated by the male hormone, testosterone.

And those are the basics of the prostate! Join me next week when we talk more about the prostate.

 

Have a topic you’d like to learn about? Why not suggest it here!