Caffeine

I am just coming down from that finals rush that us university students are all so accustomed to. Those long nights of studying and early mornings to keep studying – it gets tiring. A lot of students have a particular molecule to thank for getting them through those long days: caffeine. Whether it’s coffee, or energy drinks, students can be seen anywhere on campus chugging down these caffeinated substances. But how does this particular substance work to keep the students active and awake?

What is Caffeine?

Caffeine is a purine alkaloid, which is a particular type of chemical compound. It is found organically in Coffea arabica and Camellia sinsensis.

Coffea arabicaCamellia sinsensis

Coffea arabica is the source of coffee, while Camellia sinsensis is the source of tea.

How does caffeine affect our systems?

Caffeine can be completely absorbed by the stomach and small intestine within 45 minutes, and it takes around 3 to 4 hours just to remove half of the consumed caffeine from your system.

Caffeine stimulates our central nervous system (CNS), which is composed of our brain and spinal cord. By stimulating the CNS, the caffeine molecules fight against drowsiness and helps keep you alert. It does all of this by preventing a nucleoside, named adenosine (which is found in our DNA!), from binding to its receptors in the brain.

Adenosine usually suppresses the CNS when it binds to its receptors; this leads to general drowsiness. When caffeine binds these receptors, adenosine can no longer interact with the brain receptors which leads to a decrease in drowsiness (or increase in alertness!). Another result of caffeine binding these receptors is the stimulation of other neurotransmitters that also lead to an increase in your ability to concentrate and stay awake. These neurotransmitters include: norepinephrine, dopamine, acetylcholine and serotonin (which will be explored later).

An interesting fact about caffeine is that its half life,which is the time it takes to remove half of the consumed substance from your system, can be shortened by one’s smoking. So if you’re smoking, you’re going to need more caffeine than the average person to get relatively the same jolt of energy.

And that’s a brief summary of caffeine and its effects! Now you know how exactly caffeine works to become your savior through those long nights. Thanks caffeine, on behalf of all of us sleep-deprived students.